Thanks for the response Ankit 
I have gone through these links and these definitely help us while having an RFC calls between ECC systems.
My query is specific to IDoc since we have created an AIF Interface for our IDOC Structure and are monitoring the messages in AIF monitoring screen.
However, at the endpoint, when an IDoc is ready to be transmitted and a call is made to its RFC destination, the message somehow fails. I need to capture such failures which is not happening in AIF error handling currently.
Can anyone please let me know if the above failures can be captured? Also, please inform if I am missing something.
Thank you,
Krishnan.